Cast Update for Resident Evil: Afterlife

Milla Jovovich as Alice and clones: The primary protagonist who was previously tracked down by the Umbrella Corporation and captured in order to develop a serum from her blood. In the film she will settle her score with The Umbrella Corporation, after she let them know that she was coming after them at the end of the third film.

	Wentworth Miller as Chris Redfield: based on the video game character of the same name. He is the brother of Claire, he first appeared as one of the main protagonists in the original Resident Evil game and later as the co-protagonist of Resident Evil 5.
	Ali Larter as Claire Redfield: Very loosely based on the video game character of the same name, she plays a prominent role in Resident Evil 2 and Resident Evil Code: Veronica. In Resident Evil: Extinction, she led a convoy of survivors.
	Spencer Locke as K-Mart: renamed after the department store she was found in, K-Mart was a member of Claire Redfield's convoy of remaining survivors. She was last seen in the hijacked helicopter bound for Alaska during conclusion of Extinction.
	Alex Williams as Bilie Dyork: One of the survivors of the destruction that occurred in the previous film, "Resident Evil: Extinction", become best friend of K-Mart.
	Shawn Roberts as Albert Wesker: based on the video game character of the same name, he is a prominent antagonist in many of the video games. In the film, he is the Chairman of Umbrella. His office is in Tokyo, Japan and through holographic technology, he has regular meetings with committee members.
	Boris Kodjoe as Luther: The leader of a group of survivors who have been hiding in Los Angeles for the past few years.

Source: Wikipedia